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Hydroxyethyl starch (HES) 200/0.5 APIs, formed by acid-hydrolyzed and hydroxyethylized high-branched chain amylopectin starch, is a medium MW and low molar substitution ratio HES. Its chemical formula is poly (O-2-hydroxyethyl) starch, and the common name is HES200/0.5 (penta starch).HES solution has quick effect and strong volume expansion properties; it can maintain four hours middle strength expansion; it can be cleared away from kidney; less accumulation in plasma and tissue, least effect on coagulation; it can improve microcirculation. HES 200/0.5 solution is the most frequently used plasma substitute in Europe, and is the preferred remedy in curing and defending hypovolemia and shock.Pharmacology:Hydroxyethyl starch 200/0.5 can expand plasma volume, consequently improve the cardiac output and oxygen transport of low plasma volume and shock patient, reduce the pack of red cell and viscosity of blood plasma. Meanwhile, HES 200/0.5 has its particular pharmacology in decreasing plasma leakage and dropsy of injured capillary tube, which will benefit the critically-ill patient who will be or was in organ failurePharmacokinetics:The smaller the molar substitution ratio of HES is, the quicker it metabolize, but high C2/C6 ratio will slower the metaboly in body, accordingly decrease the effect of substitution. After the HES solution was given by intravenous infusion, the initial polymer can be separated into fractions of different molar masses. The average molecular weight in the plasma will be declined to 70-80kd rapidly, and then kept the value above the kidney threshold during therapy. The other larger molar masses will be metabolized by alpha-amylase, and then eliminated by renal excretionToxicology:There is no one dead case among all the cured beastie, even under the maximum dosage. No teratogenicity was found in the teratogenicity research on rats and rabbits, no teratogenicity and embryotoxicity was inspected under the dosage of 20ml/kg, no indication of anti-procreate and immunity-toxicity in experiment on Guinea pig. Meanwhile the experiments also proved that no mutagenicity, no carcinogenicity, no local toxicity of HES200/0.5Clinical usage:HES 200/0.5 solution is the mostly common used plasma substitute at present. It can improve the cardiac output and oxygen transport of low plasma volume and shock patient, reduce the pack of red cell and viscosity of blood plasma. Lots of clinical experiments have improved that it has beneficial effect in cardiac output, oxygen support, oxygen consume and organ function of low plasma volume and shock patient
Features:1) Applications: Vitamin A and hypolipoidemic agent can promoting fat-metabolisminliver and other tissues2) For adjusting our fatty liver and lipoidemia3) Specification: NF12Inner packing:25k
Features:1) Applications: Vitamin A and hypolipoidemic agent can promoting fat-metabolism inliver and other tissues2) For adjusting our fatty liver and lipoidemia3) Specification: NF12Inner packing:25
Features:1) Quick ignition and easy kindle2) Smokeless, odorless, specially made for indoor and outdoor use (BBQ)3) High heating energy, last for three hours plus4) Shape is small, disposable packagin
Product Name: Instant GrillPlace of Origin: ChinaFeatures:1) Quick ignition and easy kindle2) Smokeless, odorless, specially made for indoor and outdoor use (BBQ)3) High heating energy, last for three
We are the leading supplier in China for food additives, special for energy drinkingredients and sweeteners. Pls visit our website: www.elongcom.com to get moreabout our company and products. If any o
Features:1) L-carnitine is a natural, vitamin-like nutrient responsible for promoting the oxidation process of long- chain fatty acids2) Helps the body convert fatty acids into energy3) Used in medici
Features:1) Applications: L-Carnitine L-Tartrate is the ideal form of L-Carnitine for all applicationin solid forms, especially for tablets and capsules2) It is used in pharmaceutical and food applica
We are the leading supplier in China for food additives, special for energy drinkingredients and sweeteners. Pls visit our website: www.elongcom.com to get moreabout our company and products. If any o
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