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Description
Chemical Materials & Products /  Chemical Agents / 
Producer information
Company:
Guangzhou Pharmaceutical Import and Export Corporation
 
Address:
59 North Shamian Street, Liwan, Guangzhou, Guangdong, China (Mainland) Zip: 510130
 
Phone:
+86-20-81217026

Anticancer Pharmaceutical Raw Materials


Product Name: Anticancer Pharmaceutical Raw MaterialsPlace of Origin: Guangzhou, China1) Vincristine sulphate:Standard: BP 2004, USP 28, CP 2005, EP 5.0Action and indications:Vincristine sulfate is an alkaloid extracted from vinca rosea. As a cell cycle specificdrug, it can inhibit growth of neoplasm and formation of proliferating cellspindle, as a result, mitosis is stopped at its metaphase. Clinically, it issimilar to vinblastine sulfate with better effects, however, no cross toleranceis found between the two drugs. It is more effective in the treatment of variousacute leukemia, especially acute lymphoblastic leukemia. In addition, it has someeffect for malignant lymphoma, chorioepithelioma, breast carcinoma, neuroblastoma,nephroblastoma, brain tumors, lung cancer, leiomyosarcoma, cervix cancer andalimentary tract tumor.Usage:Used for preparation of vincristine sulfate for injections.Packing: 50kg/bottle2) Vinblastine sulphate:Standard: BP 2004, USP 28, EP 5.0, CP2005Action and indications:Vinblastine sulfate is an alkaloid extracted from vinca rosea. As a cell cycle specificdrug, it can inhibit growth of neoplasm and formation of proliferating cellspindle, as a result, mitosis is stopped at its metaphase. Clinically, it issimilar to vincristine sulfate in effects, no cross tolerance is found between thetwo drugs. It is more effective in the treatment of malignant lymphoma, especiallylymphoreticular cell sarcoma, Hodgkin`s disease, chorioepithelioma, breastcarcinoma, head and neck cancer, oropharynx cancer, neuroblastoma, monocytic leukemia,lung cancer, cervix cancer and alimentary tract tumors, and it has someeffect in the treatment of lymphoma, nephroblastoma and melanoma.Usage:Used for preparation of vinblastine sulfate for injections.Packing: 50kg/bottle3) Vinorelbine bitartrate:Standard: EP 5.0, USP 28, CP 2005Action and indications:Vinorelbine is a vinca alkaloid, which is prepared by extraction from vinca roseaand chemical semi-synthesis. It is the drug of choice for the treatment of smallcell lung cancer and advanced breast carcinoma. Vinorelbine has a direct activityon dynamic equilibrium of tubulin, especially on division stage of tubulin. Itinfluences on tubulin in axon only at its higher concentration and its activityon helical structure of tubulin is less the vincristine.Usage:Used for preparation of vinorelbine bitartrate for injections.Packing: 50kg/bottle4) Vindesine sulphate:Standard: BP 2004, USP 28, CP 2005, EP 5.0Action and indications:It is a semi-synthetic vinca alkaloids derivative, which can inhibit many neoplasmsof animal models and is more active than vincristine against neoplasm. It isindicated in the treatment of pulmonary carcinoma, malignant lymphoma, breast carcinoma,leukemia, germinoma, cancer of head and neck, oophoroma and soft tissuesarcoma. It exhibits a broad spectrum of in vivo antitumour activity against graftanimal tumor and has no cross-resistance with vinblastine and vincristine.Usage:Used for preparation of vindesine sulfate for injections.Packing: 50kg/bottle

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