Quick Detail: Product name Anastrozole Factory Supplying Other name Arimidex CAS register number 120511-73-1 Molecular formula C17H19N5 Molecular weight 293.37 Molecular structure Melting point 81.0~84.0¡ãC Assay 98% Product description: Arimidex (generic name is anastrozole) is a newer drug developed for the treatment of advanced breast cancer in women. It is manufactured by Zenica Pharmaceuticals and was approved for use in the United States at the end of December 1995. Specifically, Arimidex is the first in a new class of third-generation selective oral aromatase inhibitors.. It acts by blocking the enzyme aromatase, subsequently blocking the production of estrogen. Since many forms of breast cancer cells are stimulated by estrogen, it is hoped that by reducing amounts of estrogen in the body the progression of such a disease can be halted. This is the basic premise behind Nolvadex, except this drug blocks the action and not production of estrogen. The effects of Arimidex can be quite dramatic to say the least. A daily dose of one tablet (1 mg) can produce estrogen suppression greater than 80 % in treated patients. With the powerful effect this drug has on hormone levels, it is only to be used (clinically) by post-menopausal women whose disease has progressed following treatment with Nolvadex (tamoxifen citrate). Side effects like hot flushes and hair thinning can be present, and would no doubt be much more severe in pre-menopausal patients. There are some concerns with using an aromatase inhibitor such as this during prolonged steroid treatment however. While it will effectively reduce estrogenic side effects, it will also block the beneficial properties of estrogen from becoming apparent (namely its effect on cholesterol values). Studies have clearly shown that when an aromatase inhibitor is used in conjunction with a steroid such as testosterone, suppression of HDL (good) cholesterol becomes much more pronounced. Apparently estrogen plays a role in minimizing the negative impact of steroid use. Since the estrogen receptor antagonist Nolvadex is shown not to display an anti-estrogenic effect on cholesterol values, it is certainly the preferred from of estrogen maintenance for those concerned with cardiovascular health. Arimidex has another principle drawback, namely the great price of this drug. Tablets can easily sell for $10 each, becoming quite costly with regular use. Clearly the price of an ancillary drug can be much greater than the steroids themselves, a situation destined not to be popular with recreational bodybuilders. Competitors on the other hand are likely to welcome this item. It can ward off the side effects of strong androgen therapy much better than Nolvadex and/or Proviron, making heavy cycles much more comfortable. As the number of countries manufacturing this drug increases, we may be able to look forward to a reduction in price. Privately compounded versions of “liquid Arimidex” have also been formulated “for research purposes” are also available. Generic tabs are also available and these two forms represent a very cost-effective alternative for buying the brand name drug. COA and HPLC: COA: Product name Anastrozole Appearance White crystalline powder Identification IR HPLC Reactive Conform with standard IR Conform with standard HPLC Conform Solubility Freely soluble in methanol,acetone,ethanol and tetrahydrofuran.And very soluble in acetonitrile Complies Total Impurity max.0.5% 0.17% Total Unspecified Impurity max. 0.2% 0.07% Individual unspecified impurlty max. 0.1% 0.04% Related compound B max. 0.2% 0.06% Related compound C max. 0.2% 0.04% Related compound D max. 0.1% 0.05% Related compound E max. 0.1% 0.05% Limit of cyclohexane max. 0.08% ND Limit of ethylacetate max. 0.1% 0.07% Melting point 81.0~84.0¡ãC 82.5～83.2°C Water max. 0.3% 0.23% Residue on ignition max. 0.1% 0.07% Heavy Metals max.0.001% Complies Assay(HPLC) 98.0%～102.0% 98.9% HPLC:
Aromatase inhibitor AnastrozoleTreatment of breast cancerStructural formula: C17H19N5CAS NO: 120511-73-1Molecular weight: 293.37Appearance: an off-white color crystalline powderPackage: 25KG/Drum
Quick Detail: Product name Benzocaine Factory Supplying Other name Americaine;ETHYL 4-AMINOBENZOATE;ETHYL P-AMINOBENZOATE CAS register number 94-09-7 EINECS 202-303-5 Molecular formula C9H
Quick Detail: Product name Benzocaine Factory Supplying Other name Americaine;ETHYL 4-AMINOBENZOATE;ETHYL P-AMINOBENZOATE CAS register number 94-09-7 EINECS 202-303-5 Molecular formula C9H
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