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Description
Chemical Materials & Products /  Chemical Agents / 
Producer information
Company:
Future Pharmaceutical Group
 
Address:
Gaoxin Road, Xian, Shaanxi, China (Mainland)
 
Phone:
+86-29-83182005

Levodopa Extract


Other Name: L-DopaChemical Name: L-Tyrosine, 3-hydroxy-Molec. Struct.:M.F. & M.W.: C9H11NO4;197.19Physical properties: clear to white odorless and tasteless crystal or crystalline powder; needle like crystal (in water; M.P.: 276-278, 284-286; [a]13D: -13.1 degree (C=5.12, 1N hydrochloric acid); readily soluble in dilute hydrochloric acid and formic acid; soluble in water (65mg/44ml); almost insoluble in ethanol, benzene, chloroform and acetyl acetate.Plant Source: Vicia faba L.; Mucuna cochin-chinensis(Lour) A.Cheval., seed; M.semporvirens Hemsl., seed; M.birdwoodiana Tuteh., seed; Stizolobium caprtatum (Sweet) O.Kuntze.Funtions and Applications: One of the precursors for in vivo synthesis of noradrenalin and dopamine, it can raise the level of dopamine in brain tissue. As Parkinson`s disease is caused by deficiency of dopamine in brain, it is used clinically for the treatment of the disease. It can ease the symptom (exogenous dopamine cannot overcome blood-brain barrier to be effective); also effective to similar simptom caused by Mn or Co poisoning; some therapeutical effect to hepatic coma caused by acute hepatic failure. Toxicity: oral LD50 (mg/kg): mice 3650, rats >40000, rabbit 609.

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